Dr. Kristen Highland speaks with Drs. Peter Mazzone and Vickram Tejwani about the recent 2024 American Thoracic Society Conference. Topics discussed include exposure-related mutations in non-smokers' lungs, doing better at getting the right people to be screened and new tools in development like circulating tumor DNA methylation-based tools, mutation-based tools, proteins and combinations of all these things in blood. They review the need to address disparities in access to screening, a potential new medication for COPD flares, new data on eosinophilic COPD, potentially using bronchoscopes to ablate early-stage cancer and more.