This week, I am joined by microbiologist Dr. Sarkis Mazmanian, the Luis B. and Nelly Soux Professor at Caltech, to discuss the microbiome's connection to human health—especially the gut-brain axis. Dr. Mazmanian discusses his research evolution from infectious diseases to the microbiome’s role in neurodevelopment and neurodegeneration, as well as how gut mic ... Show More
Nov 20
Fasting Compilation: Leading Experts On Water-Only Fasts, Fasting Mimicking Diets & The Optimal Fasting Window For Longevity
This Fasting Compilation features Dr. Alan Goldhamer, Dr. Valter Longo, and Dr. Michael Greger to discuss the science of strategic deprivation.
We explore why visceral fat behaves like a tumor secreting inflammatory molecules that drive chronic disease. How many health condition ... Show More
1h 8m
Nov 17
Interview With An Icon: Katie Couric On The State of Media, Institutional Distrust, Cancer Advocacy & What Actually Creates Happiness
Katie Couric is a journalist and the first woman to solo-anchor a major network evening newscast.
We explore the disintermediation of news media, institutional distrust, and the fragmentation of shared truth in America. Katie shares her experiences navigating the CBS boys club, ... Show More
1h 57m
Nov 10
Tig Notaro Is Treading Water
Tig Notaro is a comedian, actor, screenwriter, producer, and co-host of the podcast Handsome. This conversation explores Tig's legendary 2012 set—delivered days after her cancer diagnosis—and how loss became her greatest teacher. We discuss her wild upbringing, choosing presence ... Show More
2h 41m
Jan 2025
Super Aging and Your Microbiome with Dr. William Li
In this episode, Dr. William Li discusses the role of your microbiome in reversing advanced diseases, the science of super-aging, and the transformative power of foods like pomegranates, sauerkraut, and walnuts. He also reveals the latest research on gut bacteria linked to extend ... Show More
1h 33m
Sep 2022
The Genetics of Estrogen, Testosterone, Detoxification and Autism with Kashif Khan
<p>This week we welcome Kashif Kahn to the Better Show to talk about Genetics. Kashif is the CEO of The DNA Company, and we were able to speak in depth with him about our pre-determinants that will impact many aspects of our lives. We began talking about DNA reports, why copy var ... Show More
1h 36m
Feb 2025
A Germ of Truth: The 263rd Evolutionary Lens with Bret Weinstein and Heather Heying
<p>In this week’s episode, we discuss the relationship between infectious and chronic disease, and between germ theory and terrain theory of disease. Pathogens are real, and exogenous treatments like antibiotics can kill them. The health of the body is affected by diet, exercise, ... Show More
1h 56m
Sep 23
203. Barbara O’Neill: On Longevity, Gut Microbiome, Immune System, and Anti-Aging Basics
Join my FREE 3-Day Water Fast Challenge - October 15th. It's the exact protocol I use with pro athletes and Fortune 500 CEOs to flush inflammation and kickstart autophagy. Sign up here! http://bit.ly/4nTILPt Your immune system is either your greatest biological asset or your weak ... Show More
1h 25m
Aug 12
191. Dr. Darshan Shah: How to Reverse Aging with Plasma Exchange and Stem Cell Therapy
Your genetics are never your destiny, even with genetic dispositions, you can prevent Alzheimer’s and optimise longevity. After my conversation with Dr. Darshan Shah of Next Health, I’m convinced we’re living through the biggest revolution in human optimisation since the discover ... Show More
1h 12m
Apr 2025
159. Dr. Will Cole: Autoimmune Crisis? Uncover Mold and Toxins Harming You
Struggling with mystery symptoms? Most people chalk up brain fog, fatigue, or joint pain to aging, but what if it’s your body screaming for help? I sat down with Dr. Will Cole to discuss autoimmune conditions, gut health, and toxicity. Here’s the truth: your symptoms might stem f ... Show More
1h 24m