In this episode of the AI Grand Rounds podcast, Dr. Eric Horvitz describes his career evolution from an interest in neurobiology to significant contributions in AI, particularly in understanding complex systems and applying AI in medicine. He discusses the shift from studying neurobiology to embracing AI and computational methods as tools for unraveling the complexities of the human mind and broader decision-making processes. Horvitz emphasizes the importance of probabilistic models and decision theory in AI, highlighting his work on bounded rationality and the challenges of interpretability in AI systems. He also reflects on the potential of AI in medicine, the necessity of responsible AI development, and the future of AI research. He suggests a blend of excitement and caution as AI technologies become increasingly integrated into various aspects of human life and decision making.