logo
episode-header-image
Feb 2024
15m 15s

Serine-129 Phosphorylation of α-Synuclei...

AMERICAN ACADEMY OF NEUROLOGY
About this episode

Dr. Jason Crowell talks with Dr. Subhojit Roy about a platform for investigating the role of serine-129 in synucleinopathies, with implications for drug development.

Read the related article in the Neuron.

Disclosures can be found at Neurology.org.

Up next
Jul 6
Navigating the Transition From Pediatric to Adult Epilepsy Care
Dr. Dara Albert talks with Dr. Scott Perry about improving the transition from pediatric to adult epilepsy care. Read the related article in Neurology® Clinical Practice. Disclosures can be found at Neurology.org. 
22m 2s
Jul 2
Communication About Uncertainty During PD Diagnostic Consultations
Dr. Greg Cooper talks with Dr. Elisabeth Kurpershoek about how clinicians communicate uncertainty during Parkinson disease diagnosis and how this impacts patient trust and understanding. Read the related article in Neurology® Clinical Practice. Disclosures can be found at Neurolo ... Show More
16m 19s
Jul 1
July 2026 Recall: Updates in Epilepsy
The July 2026 Recall features four previously posted episodes related to updates in epilepsy. The episode opens with Dr. Rosemary Dray-Spira discussing trends in prenatal exposure to antiseizure medications over the past decade. The episode continues with Dr. Page Pennell discuss ... Show More
1h 8m
Recommended Episodes
Feb 2024
Serine-129 Phosphorylation of α-Synuclein
Drs. Jason Crowell and Subhojit Roy discuss evidence that suggests phosphorylated α-synuclein might actually have a role in normal brain cell function. Show Reference: https://www.cell.com/neuron/fulltext/S0896-6273(23)00894-2?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fre ... Show More
2m 30s
Mar 2024
Cutaneous Phosphorylated Alpha-Synuclein Deposition in Dementia
Dr. Jason Crowell talks with Dr. Christopher Gibbons to discuss his paper "Cutaneous Phosphorylated Alpha-Synuclein Deposition in Dementia with Lewy Bodies and Mild Cognitive Impairment."   Show reference:  https://index.mirasmart.com/AAN2024/SearchResults.php?Program_Number=PL4. ... Show More
4m 49s
Mar 2024
Lecanemab in Alzheimer Disease
<p>Dr. Jason Crowell talks with Dr. Anelyssa D' Abreu about her recently posted NeuroByte on key features in Lecanemab. </p> <p>Watch the <a href="https://learning.aan.com/courses/62800" target="_blank" rel="noopener">NeuroByte now</a>! </p> 
4 m
Jul 2024
Understanding Apathy in Parkinson Disease - Part 2
Dr. Jason Crowell and Dr. Campbell Le Heron discuss tips and recommendations to help improve apathy in folks with Parkinson disease. Show references:  https://www.neurology.org/doi/10.1212/WNL.0000000000209301   
4m 14s
Aug 2024
The Ethical Landscape of Prodromal Parkinson Disease
Dr. Jason Crowell and Dr. Colin Hoy discuss the concept of prodromal Parkinson disease and the ethical considerations surrounding its diagnosis.  Show reference: https://www.neurology.org/doi/10.1212/WNL.0000000000209522  
2m 13s
Feb 2025
Consensus Recommendations for the Management of Neurosarcoidosis - Part 2
In part two of this series, Dr. Shuvro Roy and Dr. Giovanna S. Manzano discuss the main findings from her study on neurosarcoidosis. Show reference: https://www.neurology.org/doi/10.1212/CPJ.0000000000200429   
5m 49s
Feb 2025
Consensus Recommendations for the Management of Neurosarcoidosis - Part 1
In part one of this series, Dr. Shuvro Roy and Dr. Giovanna S. Manzano discuss the main challenges providers face when treating neurosarcoidosis.  Show reference: https://www.neurology.org/doi/10.1212/CPJ.0000000000200429  
3m 14s
Oct 2024
Neurology on the Hill
Dr. Jason Crowell talks about Neurology on the Hill and how you can get involved if you are interested. Show reference: https://www.aan.com/policy-and-guidelines/capitol-hill-report/  
1m 35s
May 2024
Long-Term Follow-Up of the LEAP Study
Dr. Vikram Karnik and Dr. Rob de Bie discuss early vs. delayed start of Levodopa in early Parkinson disease, and what it means for our clinical practice. Show reference: https://movementdisorders.onlinelibrary.wiley.com/doi/full/10.1002/mds.29796  This podcast is sponsored by arg ... Show More
1m 51s
Jul 2024
Transcobalamin Receptor Antibodies in Autoimmune Vitamin B12 Central Deficiency - Part 2
Dr. Justin Abbatemarco, Dr. Michael R. Wilson, and Dr. John Pluvinage discuss their discovery of anti-CD320 antibodies in patients with neurologic manifestations of B12 deficiency and discuss the potential implications for diagnosis and treatment.  Show reference:  https://www.sc ... Show More
2m 15s