EP 122: Building genome-scale engineered cells for biotechnology with Leslie Mitchell, Co-founder and CEO of Neochromosome| Listen on Anghami

Aug 27

EP 254: Triangulating genetic evidence and dodging bias to pick winning drug targets with Brent Richards of 5 Prime Sciences

This week on The Genetics Podcast, Patrick is joined by Dr. Brent Richards, CEO and Founder of 5 Prime Sciences and Professor of Human Genetics, Epidemiology, and Medicine at McGill University. They discuss how to triangulate different types of genetic evidence to validate a drug ... Show More

41m 54s

Aug 20

EP 253: The genetics of brain size, growth, and aging with Andrew Jackson of the University of Edinburgh

This week on The Genetics Podcast, Patrick is joined by Dr. Andrew Jackson, Programme Leader at the MRC Human Genetics Unit at the University of Edinburgh. They discuss how his lab discovered that gain-of-function DNMT3A mutations cause both microcephalic dwarfism and an accelera ... Show More

37m 17s

Aug 13

EP 252: The diagnosis that became a mission to cure rare disease: Advancing genetic medicine using AI with Stevie Ringel of Nome

This week on The Genetics Podcast, Patrick is joined by Stevie Ringel, co-founder of Nome and founder of the Kizuna Foundation. They discuss Stevie's own ultra-rare disease diagnosis and shaped his path to founding Kizuna Foundation and Nome, how Nome's AI agents help scientists ... Show More

37m 58s

May 2022

Turning Cells into Tiny Factories

Reshma Shetty is co-founder and chief operations officer of Ginkgo Bioworks. Her problem: How do you turn cutting-edge science into a sustainable business? Ginkgo is a synthetic biology company. The idea is to make industrial products -- fragrances, or food, or whatever ... Show More

16m 54s

Jul 2021

Engineering an Epigenome Editor

On today’s episode we are discussing the results and implications of a recent study that describes the creation of a new set of tools to turn off or on any region in the genome with high specificity. Host Lauren Richardson and a16z general partner Vijay Pande are joined by the ... Show More

31m 38s

Sep 2023

Business and science: What you need to know about SynBio

In this week’s series focusing on business and science, we start things off by looking at the world of synthetic biology.The industry is estimated to be worth around $30bn in the next few years, but how is that money actually made?We speak to businesses across the world to find o ... Show More

17m 28s

Mar 2024

DNA as Data Storage with Vijay Pande

Vijay Pande, founding partner of a16z Bio + Health, dives deep with a16z Podcast host Steph Smith into the potential of DNA as a data storage mechanism.This episode, a cross-post with the a16z Podcast, draws parallels between Moore's Law and the race for "Moore's Law fo ... Show More

21m 52s

Nov 2021

Genetic dreams, genetic nightmares

Professor Matthew Cobb looks at how genetic engineering became big business - from the first biotech company that produced human insulin in modified bacteria in the late 1970s to the companies like Monsanto which developed and then commercialised the first GM crops in the 1990s. ... Show More

27m 29s

Oct 2024

TWiP 244: Engineering Toxoplasma

Lilach Sheiner joins TWiP to talk about her career and her work on engineering Toxoplasma gondii secretion systems for intracellular delivery of multiple large therapeutic proteins to neurons. Hosts: Vincent Racaniello, Dickson Despommier, and Christina Naula Guest: Lilach Sheine ... Show More

49m 41s

Jun 2023

Matice Founder Jessica Whited on Harnessing Regenerative Species for Medical Breakthroughs - Ep. 198

Scientists at Matice Biosciences are using AI to study the regeneration of tissues in animals known as super-regenerators, such as salamanders and planarians. The goal of the research is to develop new treatments that will help humans heal from injuries without scarring. On the l ... Show More

39m 8s

Aug 2021

Discovery, Translation, and the State of Bio Today

On this episode, we are taking a pulse-check on the state of the intersection between biology, healthcare, and technology with two scientists that sit at another intersection, that of academia and industry: Alexander Marson and Patrick Hsu, who are professors at UC San Francis ... Show More

33m 5s

EP 122: Building genome-scale engineered...