logo
episode-header-image
Jan 2024
5m 53s

Exploring the Potential of Therapeutic P...

Eddy Joe Gutierrez, MD
About this episode

In this episode, we delve into the groundbreaking study "Influence of therapeutic plasma exchange treatment on short-term mortality of critically ill adult patients with sepsis-induced organ dysfunction." We explore how Therapeutic Plasma Exchange (TPE) could revolutionize the treatment of sepsis, a condition notoriously difficult to manage. The episode breaks down the study's methods, results, and significant implications for future clinical practice, highlighting the urgent need for further research in this promising area.

The Vasopressor & Inotrope Handbook: ⁠⁠⁠Amazon Affiliate Link⁠⁠⁠ (I will earn an extra small commission) and ⁠⁠⁠Signed/Personalized Copies⁠⁠⁠.

Citation: Kuklin V, Sovershaev M, Bjerner J, Keith P, Scott LK, Thomas OMT, Szpirt W, Rock G, Stegmayr B. Influence of therapeutic plasma exchange treatment on short-term mortality of critically ill adult patients with sepsis-induced organ dysfunction: a systematic review and meta-analysis. Crit Care. 2024 Jan 4;28(1):12. doi: 10.1186/s13054-023-04795-x. PMID: 38178170; PMCID: PMC10768220.

Up next
Aug 17
Should You Avoid the Right IJ for Central Lines in Critically Ill Patients?
In this episode of the Saving Lives Podcast, Eddy Joe breaks down a 2025 Journal of Critical Care study examining how the choice of the internal jugular vein for initial central line placement impacts outcomes when patients later need hemodialysis catheters. You'll learn why usin ... Show More
8m 27s
Aug 12
Acetazolamide + Furosemide: Boosting Diuretic Response & Fighting Alkalosis in the ICU
In this episode, we dive into a new pilot RCT exploring the addition of acetazolamide to furosemide in critically ill patients. We break down the study’s methods, findings, and practical implications for fluid management in the ICU. Could this inexpensive, decades-old drug be the ... Show More
9m 16s
Jul 19
Methylprednisolone vs. Hydrocortisone: Which Can Save More Lives in Severe Pneumonia?
In this episode of the Saving Lives Podcast, we review a July 2025 study from the Journal of Intensive Care comparing methylprednisolone and hydrocortisone for severe pneumonia treatment. The discussion focuses on how these findings may influence clinical decisions, particularly ... Show More
5m 8s
Recommended Episodes
Jul 2023
Prof. John Myburgh talks Fluids, Catecholamines, South Africa and a little bit of Research.
In this episode, we have the honor of speaking with Professor John Myburgh, a former South African physician and researcher who has dedicated his life to improving the field of critical care medicine. Professor Myburgh has made significant contributions to the field of fluid resu ... Show More
33m 24s
Mar 2024
Episode 19: Extracorporeal Blood Purification in the Context of Multiorgan Support: Current Role and Best Practices
Episode 19 is the third episode in KDIGO's three-episode series on acute kidney injury (AKI), hosted by Dr. Kathleen Liu (University of California at San Francisco, United States). In this episode, Dr. Liu and Dr. Claudio Ronco (International Renal Research Institute of San Borto ... Show More
11 m
Feb 2025
The Highs and Lows of Treating Osteoporosis in Dialysis Patients
Osteoporosis in dialysis patients is a challenging yet crucial aspect of kidney care, often overshadowed by more familiar concerns. This episode of Life as a Nephrology Professional brings together experts to uncover the unique dynamics of bone disease in end-stage kidney disease ... Show More
46m 5s
Jul 2024
Ethical Considerations in CAR T-cell Therapy
Welcome to a thought-provoking episode of our podcast series, where we dive into the ethical and practical challenges of CAR T-cell therapy with Professor Marie José Kersten from Amsterdam University Medical Centers.In this episode, our host Dr Isabel Olivera engages in a deep di ... Show More
21m 56s
Oct 2024
Hemophilia Part 2
In the next podcast episode, we will continue our talk on hemophilia. Specifically the treatment of hemophilia. We’ll discuss the different types of therapy available, from traditional factor replacement to emerging gene-techniques. Join Dr. Niket Sonpal as he helps us manage hem ... Show More
9m 17s
Jun 9
Episode 124: Inside the Chest: NodeAI and the Future of Endobronchial Ultrasound
In this episode, we sit down with Dr. Wael Hanna, thoracic surgeon and founder of NodeAI, a pioneering startup transforming the evaluation of mediastinal lymph nodes through artificial intelligence. Dr. Hanna shares the inspiration behind NodeAI, the clinical problem it aims to s ... Show More
19m 48s
May 15
Essentials: Understanding & Healing the Mind | Dr. Karl Deisseroth
In this episode of Huberman Lab Essentials, my guest is Dr. Karl Deisseroth, M.D., Ph.D., a clinical psychiatrist and professor of bioengineering and of psychiatry and behavioral sciences at Stanford University. We discuss his experiences as a clinician treating complex psychiatr ... Show More
43m 45s
Jan 2025
Catheter-Related Bloodstream Infection (CRBSI): An Update on Prevention Strategies
Hemodialysis catheter-related bloodstream infection (CRBSI) is an ongoing challenge. This podcast features a discussion between healthcare professionals and patient discussing methods aimed at reducing CRBSI risk. The panelists will also provide an update on innovations in the ar ... Show More
23m 11s
Jun 2024
EM Quick Hits 57 – HIV Diagnosis, Failed Paradigm of STEMI Criteria, Poisoned Patient Airway Management, Spontaneous Bacterial Peritonitis, DIY Investments
In this month's EM Quick Hits podcast: Megan Landes on the importance of diagnosing HIV in the ED, Jesse McLaren on the failed paradigm of STEMI criteria and ECG tips to identify acute coronary occlusion, Anand Swaminathan on evidence for non-invasive airway management in the poi ... Show More
58m 3s
Mar 2025
Myelodysplastic Syndrome (MDS)
Ninja Nerds,Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we explore Myelodysplastic Syndrome (MDS), a group of hematologic disorders characterized by ineffective hematopoiesis and a risk of progression to acute myeloid leukemia (AML). We also discuss the ... Show More
26m 35s