Trial of the Week: CRASH-3
Special Guest: Ruben Santiago, PharmD, BCPS, BCCCP
Ruben Santiago joins me to discuss the landmark article “Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with
acute traumatic brain injury (CRASH-3)” published in Lancet.
We review the history of TXA use in trauma, what ... Show More
Jan 2026
RSI Trial Deep Dive
Special Guests: Matthew Semler, MD & Nicole Acquisto, PharmD, FASHP, FCCM, FCCP Join us as we do a deep dive into the RSI trial, published in NEJM in Dec 2025. Previous RCTs, study development timeline, guideline recommendations, study methodology and findings, answering listener ... Show More
1h 34m
Mar 2025
BIG T Trauma Series Ep. 21: All Things TXA
Join Patrick Georgoff as he welcomes Dr. Gene Moore and Dr. Ian Roberts, two giants in trauma surgery and epidemiology, to discuss tranexamic acid (TXA) in trauma care. Dr. Moore, a legendary trauma surgeon and researcher, and Dr. Roberts, the architect of the CRASH trials, break ... Show More
49m 21s
<p><strong>Contributor: Nick Hatch, MD</strong></p> <p><strong>Educational Pearls:</strong></p> <ul> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">In the setting of traumatic injury, tranexamic acid (TXA) is given to stabilize clots which minimizes ... Show More
