Will OpenAI Kill All Startups?

Paul Gross and his team at Remora are trying to do something that’s never been done before.They're building mobile carbon capture devices for commercial trucks and trains—capturing CO2 from moving vehicles before it enters the atmosphere, then turning those emissions into revenue ... Show More

Jordan Fisher is the co-founder & CEO of Standard AI and now leads an AI alignment research team at Anthropic. In his talk at AI Startup School on June 17th, 2025, he frames the future of startups through questions rather than answers—asking how founders should navigate a world w ... Show More

Ever wonder what it actually takes to train a frontier AI model?YC General Partner Ankit Gupta sits down with Nick Joseph, Anthropic's Head of Pre-training, to explore the engineering challenges behind training Claude—from managing thousands of GPUs and debugging cursed bugs to b ... Show More

Sylvain Duranton helps companies build AI-enabled businesses. As the the global leader of BCG X, he has a front row seat to the generative AI revolution. He discusses the industries likely to face the most disruption, the future of work, and how generative AI can help solve chall ... Show More

This Week in Startups is brought to you by… Hubspot for Podcast Network. Looking to up your marketing game? Check out HubSpot's Chatbot Builder:  https://clickhubspot.com/s0u Hubspot YouTube Channel is available on all your favorite podcast apps. Chatbot Tutorial here: https: ... Show More

Artificial intelligence is the new electricity. The fifth industrial revolution. And companies that go all-in on AI are reaping the rewards. So how do you make that happen? That big question — how? — is explored by Nitin Mittal, Principal at Deloitte, one of the world’s largest p ... Show More

Discover the motivations behind OpenAI's substantial $100M investment in AI startups, unraveling how this move shapes the future of tech innovation and impacts burgeoning companies in the AI landscape. Get on the AI Box Waitlist: AIBox.ai Join our ChatGPT Community: Facebook ... Show More

This Week in Startups is presented by: Vanta. Compliance and security shouldn't be a deal-breaker for startups to win new business. Vanta makes it easy for companies to get a SOC 2 report fast. TWiST listeners can get $1,000 off for a limited time at vanta.com/twist. Trovata. ... Show More

Dalton Caldwell is Managing Director and Group Partner at Y Combinator. Prior to YC, he was the co-founder and CEO of imeem (acquired by MySpace in 2009) and the co-founder and CEO of App.net. During his time at YC, he’s advised more than 35 YC unicorns, including DoorDash, Ampli ... Show More

This week on Equity, Alex was joined by Nathan Baschez, the CEO and founder of Lex, an AI-infused online writing tool that recently raised capital. Together, we're talking through a few key topics that have been top of mind in recent months:How many AI-powered, or AI-using writin ... Show More

Brought to you by Linear—The new standard for modern software development. | Eppo—Run reliable, impactful experiments. | Pando—Always-on employee progression.—Gustaf Alströmer is a Group Partner at Y Combinator, where he’s worked with over 600 startups in his 6.5 years there. He’ ... Show More

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Miguel Armaza is joined by Michael Seibel and Dalton Caldwell, Managing Directors and Group Partners at Y Combinator (YC). YC is one of the most successful startup accelerators and venture capital funds, and since March 2005 has helped over 5,000 startup founders build and launch ... Show More