logo
episode-header-image
Jul 2023
38m 18s

Episode 58 - Mitochondrial Diseases and ...

Neurology Exam Prep Podcast
About this episode

A review of the selected mitochondrial diseases that affect the nervous system, with Drs. Aaron Bower and Jeremy Moeller.

Note: This podcast is intended solely as an educational tool for learners, especially neurology residents. The contents should not be interpreted as medical advice.

References

1. Davis RL, Liang C, Sue CM. Mitochondrial diseases. Handb Clin Neurol 2018;147:125-141.

2. Ng YS, Bindoff LA, Gorman GS, et al. Mitochondrial disease in adults: recent advances and future promise. Lancet Neurol 2021;20:573-584.

3. Orsucci D, Caldarazzo Ienco E, Rossi A, Siciliano G, Mancuso M. Mitochondrial Syndromes Revisited. J Clin Med 2021;10.

4. Buajitti E, Rosella LC, Zabzuni E, Young LT, Andreazza AC. Prevalence and health care costs of mitochondrial disease in Ontario, Canada: A population-based cohort study. PLoS One 2022;17:e0265744.

5. Tetsuka S, Ogawa T, Hashimoto R, Kato H. Clinical features, pathogenesis, and management of stroke-like episodes due to MELAS. Metab Brain Dis 2021;36:2181-2193.

6. Shemesh A, Margolin E. Kearns Sayre Syndrome. StatPearls. Treasure Island FL: © 2022, StatPearls Publishing LLC., 2022.

7. Davila-Siliezar P, Carter M, Milea D, Lee AG. Leber hereditary optic neuropathy: new and emerging therapies. Curr Opin Ophthalmol 2022;33:574-578.

8. Shemesh A, Sood G, Margolin E. Leber Hereditary Optic Neuropathy (LHON). StatPearls. Treasure Island FL: © 2022, StatPearls Publishing LLC., 2022.

9. Velez-Bartolomei F, Lee C, Enns G. MERRF. In: Adam MP, Everman DB, Mirzaa GM, et al., eds. GeneReviews(®). Seattle WA: © 1993-2023, University of Washington, Seattle. GeneReviews is a registered trademark of the University of Washington, Seattle, 1993.

10. Hameed S, Tadi P. Myoclonic Epilepsy and Ragged Red Fibers. StatPearls. Treasure Island FL: © 2022, StatPearls Publishing LLC., 2022.

11. Hirano M, Carelli V, De Giorgio R, et al. Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE): Position paper on diagnosis, prognosis, and treatment by the MNGIE International Network. J Inherit Metab Dis 2021;44:376-387.

12. Rahman S, Copeland WC. POLG-related disorders and their neurological manifestations. Nat Rev Neurol 2019;15:40-52.

Up next
Dec 2024
Episode 74 - Neurosyphilis
A discussion of neurological manifestations of syphilis with Drs. Aaron Bower and Harry Sutherland.ReferencesPeeling RW, Mabey D, Kamb ML, Chen XS, Radolf JD, Benzaken AS. Syphilis. Nat Rev Dis Primers 2017;3:17073.Hook EW, 3rd. Syphilis. Lancet 2017;389:1550-1557.Ghanem KG, Ram ... Show More
28m 45s
Dec 2024
Episode 73 - Episodic Vertigo
An overview of episodic vertigo syndromes with Drs. Anand Bery and David Hale. Hosted by Dr. Jeremy Moeller Note: This podcast is intended solely as an educational tool for learners, especially neurology residents. The contents should not be interpreted as medical advice. 
46m 51s
Oct 2024
Episode 72 - Surgical Treatment of Epilepsy
A discussion of the surgical treatment of epilepsy with Drs. William Signorile and Jeremy Moeller. Note: This podcast is intended solely as an educational tool for learners, especially neurology residents. The contents should not be interpreted as medical advice. 
45m 41s
Recommended Episodes
Dec 2024
Top Takeaways from 2024: Interventional Cardiology with Deepak L. Bhatt, MD, MPH, MBA, FACC
In this interview, Deepak L Bhatt, MD, MPH, MBA, FACC, and Alison L. Bailey, MD FACC, discuss the Top Interventional Takeaways from 2024. Dr. Bhatt discusses the CLEAR SYNERGY, DanGer Shock, EARLY TAVR trials and more.   Jolly SS, d’Entremont MA, Lee SF, et al., for the CLEAR Inv ... Show More
16m 1s
Mar 2022
#30 Myotonic dystrophy
Sam chats to neurology SpR Dr Tom Minton about Myotonic dystrophy, covering every possible clinical sign whether it's a peripheral nerve examination or a cranial nerve examination. Tom also tackles Reg Against the Machine on a topic very close to his heart....you'll have to liste ... Show More
36m 22s
Jun 2023
#63 Motor Neurone Disease
Dr Alex Thompson, honorary consultant neurologist at Oxford University Hospitals NHS Trust, joins Sam for today's episode looking at motor neurone disease in PACES. We talk through the history, examination signs, differential diagnoses, investigations and management of this condi ... Show More
53m 33s
Sep 2024
Semaglutide and NAION
Dr. Peter Quiros joins host Dr. Amanda Redfern to discuss the recent JAMA Ophthalmology article "The Risk of Nonarteritic Anterior Ischemic Optic Neuropathy in Patients Prescribed Semaglutide," the first study to report a possible association between semaglutide (Wegovy, Ozempic, ... Show More
13m 41s
Oct 2024
“Not Tonight”—The Impact of Female Sexual Dysfunction on Women’s Well-Being - Frankly Speaking Ep 404
Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-405 Overview: It’s estimated that between 40%-60% of women report some degree of sexual dysfunction, which can have a significant ... Show More
16m 17s
Jul 2023
Prof. John Myburgh talks Fluids, Catecholamines, South Africa and a little bit of Research.
In this episode, we have the honor of speaking with Professor John Myburgh, a former South African physician and researcher who has dedicated his life to improving the field of critical care medicine. Professor Myburgh has made significant contributions to the field of fluid resu ... Show More
33m 24s
Aug 2024
MS & The Spinal Cord
The spinal cord serves as the main communication highway between the brain and body. Did you know that 80% of people with multiple sclerosis have spinal cord lesions on MRI? These lesions can disrupt specific neural pathways, leading to common MS symptoms like numbness, weakness, ... Show More
39m 50s
Jan 2025
JVS CIT Editorials and Abstracts - Dec 2024/Jan 2025
In this episode, we spotlight editorials and abstracts from the Journal of Vascular Surgery Cases, Innovations, and Techniques (JVS-CIT). Editorials and Abstracts are read by members of the SVS Social Media Ambassadors. Guests: Dr. Gregory Magee, MD (@gregamagee) The past, presen ... Show More
56m 3s
Oct 2024
#98 Cerebellar syndrome
This week Sam welcomes along Dr Yezen Sammaraiee to help us tackle cerebellar syndrome in PACES. Yezen is CEO & Founder of popular revision resource Quesmed. Along with that he is also a neurology registrar, currently on sabbatical to focus on growing the Quesmed brand! We discus ... Show More
42m 13s
Apr 15
Pediatrics Research Roundup, Difficult Conversations and Congenital Syphilis – Ep. 242
In this episode Rachel Moon, MD, FAAP, associate editor of digital media for the journal Pediatrics, shares a research roundup from the April issue. David Hill, MD, FAAP, and Joanna Parga-Belinkie, MD, FAAP, also speak with Adam Ratner, MD, MPH, FAAP, and Nitya Shah, MD, FAAP, ab ... Show More
31m 30s