logo
episode-header-image
Jul 2023
31m 59s

Circadian rhythms and epilepsy Part I: D...

ILAE
About this episode

 The cyclic properties of seizures have been known for more than 100 years, but does everyone with epilepsy have a seizure pattern? What can be learned from seizure diaries, RNS data, and animal models, and how can this information guide further research and clinical care? Dr. Laurent Sheybani talks with Dr. Mark Quigg about circadian rhythms in epilepsy.

Selected publications:
Electrocorticographic events from long-term ambulatory brain recordings can potentially supplement seizure diaries - Quigg M, et al. (2020) Epilepsy Research

Circadian and ultradian patterns of epileptiform discharges differ by seizure-onset location during long-term ambulatory intracranial monitoring - Spencer DC, et al. (2016) Epilepsia

Interrater reliability in interpretation of electrocorticographic seizure detections of the responsive neurostimulator - Quigg M, et al. (2015) Epilepsia

Variation of seizure frequency with ovulatory status of menstrual cycles - Herzog AG, et al. (2011) Epilepsia

Is there a circadian variation of epileptiform abnormalities in idiopathic generalized epilepsy? Pavlova MK, et al. (2009) Epilepsy & Behavior

Support the show

Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice.

Let us know how we're doing: podcast@ilae.org.

The International League Against Epilepsy is the world's preeminent association of health professionals and scientists, working toward a world where no person's life is limited by epilepsy. Visit us on Facebook, X (Twitter), Instagram, and LinkedIn.

Up next
Jul 7
ILAE Updated seizure classification: Dr. Sandor Beniczky
Send comments and feedbackILAE's updated seizure classification position paper was published in Epilepsia in April 2025. Sharp Waves talked with Dr. Sandor Beniczky about the updates and how they will impact research and clinical care.The position paper is open access and availab ... Show More
13m 1s
Jun 23
Documentary filmmaker confronts epilepsy in a new memoir: Stacia Kalinoski
Send comments and feedbackSeizures cost Stacia Kalinoski her career in broadcast journalism and forced her to give up running. In her new memoir, Kalinoski recounts her journey from first seizure in college to epilepsy surgery years later, describing her seizures, struggles with ... Show More
15m 3s
Jun 9
Work-life balance: Dr. Sheryl Haut
Send comments and feedbackWork-related stress and burnout are common in physicians, with rates of burnout estimated between 25% and 60%. These stresses impact physician health, patient care, and health care systems as a whole. Sharp Waves spoke with Dr. Sheryl Haut about strategi ... Show More
22m 21s
Recommended Episodes
Jun 2024
June 2024 Neurology Recall: Topics in Epilepsy
The June 2024 replay features four previously showcased episodes on topics in epilepsy. The episode begins with Dr. Genevieve Rayner and Eliza Honybun discussing the relationship between prenatal antiseizure medication exposure and adverse postnatal neurodevelopmental outcomes. T ... Show More
1h 5m
Feb 2023
Ep 112 Epilepsy: It’s always the phlegm
Only our second episode of the season and we’re already getting in over (and inside) our heads with one of the biggest topics we’ve taken on yet: epilepsy. In this episode, we navigate the constantly changing definitions of epilepsy, make our way through the many different types ... Show More
1h 38m
May 2024
Seizure Recurrence in Generalized Epilepsy After Switching Away From Valproate
Dr. Halley Alexander talks with Dr. Emanuele Cerulli Irelli about the research on seizure recurrence in women with idiopathic generalized epilepsy who switch from valproate to another medication. Read the related article in Neurology. This podcast is sponsored by argenx. Visit ww ... Show More
12m 50s
Jun 2023
July 2023 Neurology Recall: Social Determinants of Health in Neurology
The July 2023 replay of past episodes showcases five interviews on social determinants of health in neurology. The episode begins with an interview with Dr. Heather Leeper on the links between pain and depression with unemployment due to CNS cancer. The episode continues with an ... Show More
1h 3m
Oct 2021
A Neurologist’s Take on Syncope
Guest: Paola Sandroni, M.D., Ph.D. Host: Amit K. Ghosh, M.D. (@AmitGhosh006) Syncope is defined as the sudden and transient loss of consciousness and postural tone due to global reduction of blood flow to the reticular activating system. Syncopal episodes are followed by a rapid ... Show More
29m 9s
May 2024
Idiopathic Generalized Epilepsy - Part 5
Dr. Irfan Sheikh finishes out his five-part series about idiopathic generalized epilepsy with a discussion of epilepsy with generalized tonic-clonic seizures alone. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information.   
2m 37s
May 2024
Unrecognized Focal Non-Motor Seizures in Adolescents
Dr. Halley Alexander talks with Drs. Jacqueline French and Nora Jandhyala about investigating ED recognition of motor vs. non-motor seizures and its effect on the management and treatment of focal epilepsy in adolescents. Read the related article in Neurology. Disclosures can be ... Show More
17m 30s
Oct 2023
November 2023 Neurology Recall: Topics in Stroke
The November 2023 replay of past episodes showcases five interviews on topics in stroke. The episode begins with an interview with Dr. Imogene Scott on prehospital telestroke vs paramedic scores to accurately identify stroke reperfusion candidates. The episode continues with an i ... Show More
1h 35m
Jun 2024
Mortality in a Danish NMO Cohort
Dr. Justin Abbatemarco talks with Prof. Zsolt Illes about the mortality of patients with AQP4 antibody–seropositive neuromyelitis optica spectrum disorder compared with that in the general population. Read the related article in Neurology.  This podcast is sponsored by argenx. Vi ... Show More
18m 40s
Mar 2024
Effectiveness of Seizure Dogs
Dr. Halley Alexander and Dr. Valérie van Hezik-Wester discuss whether people living with severe medically refractory epilepsy (PSRE) benefit from a seizure dog. Show reference: https://www.neurology.org/doi/10.1212/WNL.0000000000209178 
2m 12s