logo
episode-header-image
Jun 2023
19m 11s

Audio long read: ‘Almost magical’ — chem...

SPRINGER NATURE LIMITED
About this episode

In the past two years, there has been an explosion in the number of papers published relating to 'skeletal editing', a technique that allows chemists to precisely edit a molecule by deleting, adding or swapping single atoms in its core.


Although many of these methods are early in development, researchers hope skeletal editing could revolutionize how organic chemists design molecules, dramatically speeding up the drug-discovery process.


This is an audio version of our Feature: ‘Almost magical’: chemists can now move single atoms in and out of a molecule’s core




Hosted on Acast. See acast.com/privacy for more information.

Up next
Aug 20
Fusion energy gets a boost from cold fusion chemistry
00:46 Electrochemical fusionResearchers have used electrochemistry to increase the rates of nuclear fusion reactions in a desktop reactor. Fusion energy promises abundant clean energy, but fusion events are rare, hindering progress. Now, inspired by the controversial claim of col ... Show More
19m 57s
Aug 15
Controversial climate report from Trump team galvanizes scientists into action
In this Podcast Extra, we discuss a report released by the US Department of Energy, which concluded that global warming is “less damaging economically than commonly believed”. However, many researchers say that the report misrepresents decades of climate science.We discuss how sc ... Show More
13m 5s
Aug 13
Sun-powered flyers could explore the mysterious mesosphere
00:46 Tiny solar flyerResearchers have used a phenomenon known as thermal transpiration to create a solar-powered flying device that can stay aloft without any moving parts. The diminutive device, just one centimetre across, consists of two thin, perforated membranes that allow a ... Show More
31m 53s
Recommended Episodes
Feb 2024
C&EN Uncovered: The small-molecule drug renaissance
As the science of drug discovery has grown in scale and gotten more complicated, so have the drug molecules themselves. But there’s a promising class of drugs made of just a handful of atoms that punch above their weight by leveraging the natural chemistry of the cell. Recent dis ... Show More
19m 56s
Feb 2018
Richard Henderson zooms in on the molecules of life
What once took decades, now takes days, thanks to an astonishingly powerful new technique invented by Richard Henderson, winner of the 2017 Nobel Prize for Chemistry. Richard grew up in a remote village in the Scottish borders exploring the countryside and reading the weekly bund ... Show More
29m 32s
Jun 2019
How Did Alchemy Create Chemistry?
Alchemists may have never turned lead into gold, but they did create the field of chemistry. Learn how the study of alchemy worked in this episode of BrainStuff.  Learn more about your ad-choices at https://www.iheartpodcastnetwork.comSee omnystudio.com/listener for privacy infor ... Show More
6m 44s
Feb 2023
Science on ice
Pull on an extra layer and stay toasty whilst Science in Action braces for a deep freeze. Whilst we know plenty about the ice on the Earth’s poles, Roland is on a chilling journey to see what can be found in deep space. Professor Christoph Salzmann and Professor Andrea Sella at U ... Show More
33m 25s
Aug 2021
Chiara Marletto, "The Science of Can and Can't: A Physicist's Journey Through the Land of Counterfactuals" (Viking, 2021)
There is a vast class of things that science has so far almost entirely neglected. They are central to the understanding of physical reality both at an everyday level and at the level of the most fundamental phenomena in physics, yet have traditionally been assumed to be impossib ... Show More
1h 8m
Sep 2022
Chemputers & The Future of Chemistry
Prof. Lee Cronin, Regius Chair of Chemistry in the School of Chemistry at the University of Glasgow joins Jonathan to discuss working on taking the guesswork out of creating the pharmaceuticals that we depend on through the use and development of 'Chemputers', a new method that i ... Show More
43m 46s
Dec 2022
The Science of Magnetism
Dr Chris Smith and the Naked Scientist team present the latest science news, analysis and breakthroughs.In today’s programme: A breakthrough in nuclear fusion: what’s happened and what does this mean in practical terms? A new way to stop your glasses fogging up during this cold s ... Show More
51m 15s
Oct 2014
Elspeth Garman on crystallography
Jim al-Khalili talks to Professor Elspeth Garman about a technique that's led to 28 Nobel Prizes in the last century.X- ray crystallography, now celebrating its 100th anniversary, is used to study the internal structure of matter. It may sound rather arcane but it's the reason we ... Show More
27m 23s
Sep 2021
Deux particules mettent les physiciens en PLS
Einstein aurait tiré la langue devant ce problème. Car il y a comme un couac dans la physique. Le comportement de deux particules subatomiques (le muon et le méson B) échappe aux règles du modèle standard, qui cochait jusqu'alors toutes les cases expliquant le fonctionnement de l ... Show More
15m 7s
Apr 2019
Will we ever know what the universe is made of?
We are all made of particles – but what are particles made of? It’s a question that’s been perplexing scientists for centuries - for so long, in fact, that listener Doug in Canada wants to know if there’s a limit to how much they can ever discover. CrowdScience heads out to CERN, ... Show More
35m 25s