logo
episode-header-image
Mar 2023
28m 21s

Julie Williams on Alzheimer’s disease

Bbc Radio 4
About this episode

There are almost a million people in the UK living with dementia, and Alzheimer’s is the most common form. But the disease actually starts long before any noticeable symptoms appear, and over the past decade, studies have shown that it is much more complex than previously thought.

Julie Williams has been at the forefront of this effort, uncovering the genes that make us susceptible, and has transformed our understanding of this devastating disease. She has brought researchers together to create bigger datasets and more powerful studies. Her current work with scientists from other fields, like immunology and computational biology, is looking at the mechanisms underlying Alzheimer’s disease.

Julie tells Jim about her early interest in science, her time as Chief Scientific Advisor to the Welsh government, and her belief in ‘team science’ – collaborating and sharing research findings across international borders and disciplines.

Produced by Florian Bohr

Up next
May 26
Dean Lomax on discovering ichthyosaurs and defying nay-sayers
Have you ever been told you aren't good enough to do something, then gone ahead and proved the naysayers wrong by doing it anyway - in glorious, headline-grabbing style? That is the satisfying story of Dr Dean Lomax. Dean grew up in Doncaster with a passion for fossils but after ... Show More
28m 24s
May 19
Helen Hastie on the future of human-robot relations
What if robots of the future weren’t just clever machines, performing tasks in isolation, but trusted teammates you could have a chat with? That could respond naturally to conversational cues and even explain their work? Making this relationship a reality is a focus for Helen Has ... Show More
28m 22s
May 12
Seth Berkley on the importance of vaccinating the world
Dr Seth Berkley is an epidemiologist and global health leader whose career has been shaped by one central problem: vaccines save lives, but only if people can actually get them.His 40-year career has spanned the global, from helping to build Uganda’s first HIV surveillance system ... Show More
28m 24s
Recommended Episodes
Sep 2021
What Causes Alzheimer's?
<p>The human brain is mysterious and complicated. So much so, one might be tempted to argue that it only makes sense that we still don't have a cure for Alzheimer's disease, despite decades of research. But this isn't the whole story. We've partnered with Vox's <em>Unexplainable< ... Show More
29m 54s
Oct 2021
Early Alzheimer's Alert
Marnie Chesterton hears of a simple test for the earliest signs of Alzheimer's disease. She finds out about UK scientists using robots to map radiation at Chernobyl, and talks to Merlin Sheldrake about fungi.Roland Pease travels to Bath University to meet scientists who may have ... Show More
32m 4s
Aug 2023
What difference could new Alzheimer’s disease drugs make?
Until recently, breakthroughs in treating Alzheimer’s disease were non-existent. But two new drugs have shown promise in moderately slowing memory and thinking problems for people with early-stage disease. While welcoming the idea of a ‘new era’ for treating Alzheimer’s disease, ... Show More
28m 37s
Feb 2021
What you can do to prevent Alzheimer's | Lisa Genova
Alzheimer's doesn't have to be your brain's destiny, says neuroscientist and author of "Still Alice," Lisa Genova. She shares the latest science investigating the disease -- and some promising research on what each of us can do to build an Alzheimer's-resistant brain. Hosted on A ... Show More
14m 6s
May 2022
Cortex Anatomy and Alzheimer's Disease
There are 6 million Americans living with Alzheimer's Disease. This program explains the latest understanding of the anatomy and functions of the brain and how it relates to neurological diseases. Dr. Gil Rabinovici is at the forefront of novel diagnostic testing to detect Alzhei ... Show More
1h 24m
Jul 2023
How close are we to ending Alzheimer's?
A new drug, Donanemab, has been hailed as a turning point in the fight against Alzheimer's after a global trial confirms it slows cognitive decline.One trial was shown to have “significantly slowed” the progression of the disease—by 35%.Earlier this year, Lecanemab, the first dru ... Show More
48m 39s
Jan 2020
The silence of the genes
In summer of 2019 NICE approved the use of a completely new class of drugs: the gene silencers. These compounds are transforming the lives of families who have rare debilitating – and sometimes fatal - diseases such as amyloidosis and porphyria. James Gallagher, BBC Health and Sc ... Show More
27m 21s
Feb 2024
#512: Alzheimer's Disease – Drs. Ayesha & Dean Sherzai
tail spinning
1h 10m