FDA D.I.S.C.O. Burst Edition: FDA approv...

Listen to a soundcast of the February 9, 2023, FDA approval of Jemperli (dostarlimab-gxly) for mismatch repair deficient (dMMR) recurrent or advanced endometrial cancer that has progressed on or following a prior platinum-containing regimen. 

Listen to a soundcast of the February 3, 2023, FDA approval of Trodelvy (sacituzumab govitecan-hziy) for HR-positive breast cancer. 

Listen to a soundcast of the January 27, 2023, FDA approvals of Jaypirca (pirtobrutinib) for relapsed or refractory mantle cell lymphoma, and Orserdu (elacestrant) for ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer. 

In this episode Dr. Timothy Cripe and Dr. Brenda Weigel are joined by FDA's Dr. Nicole Drezner, pediatric oncologist and the Deputy Division Director of the Division of Oncology 2 who led the FDA review and publication on the approval of DFMO. Listen in on the discussion surround ... Show More

New FDA-approved therapies for BCG-refractory non-muscle invasive bladder cancer (NMIBC)–where do they fit in the treatment algorithm, and how do you administer them? This installment of the 2025 NMIBC Creator Weekend™ series features host Dr. Bogdana Schmidt, assistant professor ... Show More

In this episode, Michael and Josh take a dive into the world of driver mutations, looking at two of the most clinically consequential: EGFR and ALK mutations. The work done in these areas has led to treatments that represent incredible advances over chemotherapy. How incredible? ... Show More

<p>Dr. Gordon Smith talks with Dr. Suma Babu about a newly approved treatment for ALS that is associated with a mutation in the superoxide dismutase 1 (SOD1) gene.</p> <p>Read the related article on the <a href= "https://www.fda.gov/drugs/news-events-human-drugs/fda-approves-trea ... Show More

In this debut episode of The ASCO Post Podcast, experts in breast, prostate, and lung cancers and multiple myeloma provide clinical insights about selected studies presented at the recent ASCO Annual Meeting, plus news from the FDA.To learn more, visit ascopost.com/podcasts."}" d ... Show More

This episode examines CAR T-cell therapy’s early successes, broader promise, and emerging risks, as the FDA considers reports of occasional secondary cancers. A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2400701. 

The FDA authorized the first new versions of the Covid-19 vaccines since they were introduced in late 2020, and the updated formulations target the newest Omicron subvariants. Dr. Abdul El-Sayed, epidemiologist and host of Crooked’s “America Dissected,” tells us what we need to k ... Show More

Sarcoidosis (1:30), compression therapy in venous ulcers (4:30), FilmArray GI panel (6:30), medications for alcohol use disorder (10:00), removing erroneous penicillin allergy labels (14:50), and tadalafil for benign prostatic hyperplasia (16:50).