logo
episode-header-image
Jan 2023
10m 44s

The Case of the Incredibly Long-Lived Mo...

WIRED
About this episode
Scientists kept the rodents’ immune T cells active four times longer than mice can live—with huge implications for cancer, vaccination, and aging research. Thanks for listening to WIRED. Check back in tomorrow to hear more stories from WIRED.com.  
Up next
Sep 2024
Introducing WIRED's Gadget Lab!
Although we paused on publishing narrated versions of WIRED articles in this feed, you will still hear the latest in tech from the WIRED team. On WIRED's Gadget Lab, you'll find hosts Lauren Goode and Michael Calore tackling the biggest questions in the world of tech with knowled ... Show More
43s
Jul 2024
Open Source AI Has Founders—and the FTC—Buzzing
DC went to YC to talk OS. 
8m 46s
Jul 2024
Bitcoin Bros Go Wild for Donald Trump
At the Bitcoin 2024 conference in Nashville, Trump told crypto enthusiasts exactly what they want to hear. 
12m 44s
Recommended Episodes
Dec 2023
Cat parasite Toxoplasma tricked to grow in a dish
In this episode:00:48 A new way to grow a tricky parasite in the labToxoplasma gondii, the parasite that causes the zoonotic disease toxoplasmosis, has a complex, multi-stage life cycle. Some of these stages will only grow in the intestines of cats, making it difficult to study. ... Show More
25m 48s
Oct 2023
Gene edits move pig organs closer to human transplantation
In this episode:00:46 Engineered pig kidneys show transplantation promiseKidneys from genetically-engineered miniature pigs have been transplanted into non-human primates, in some cases keeping the animals alive for more than a year. Using CRISPR, a team made dozens of edits to t ... Show More
21m 4s
Feb 2024
Cancer's power harnessed — lymphoma mutations supercharge T cells
In this episode:0:46 Borrowing tricks from cancer could help improve immunotherapyT cell based immunotherapies have revolutionised the treatment of certain types of cancer. However these therapies — which involved taking someone’s own T cells and reprogramming them to kill cancer ... Show More
35m 23s
Sep 2023
Why does cancer spread to the spine? Newly discovered stem cells might be the key
In this episode:00:45 A new insight into cancers' selective spreadCancer cells can spread to bones in the late stages of disease and in many cancers, cells actually preferentially metastasise to the spine. The reason for this has been a puzzle to researchers for years, but now a ... Show More
23m 42s
Dec 2022
What Science Tells Us About Living Longer
Scientists are hard at work trying to understand what causes aging and how to help people stay healthy for longer. Biologist Matt Kaeberlein breaks down the science of longevity and tells us how he’s using a robot to test 100,000 aging interventions a year on microscopic worms an ... Show More
29m 38s
Aug 2022
Audio long read: Hybrid brains – the ethics of transplanting human neurons into animals
The development of brain chimaeras – made up of human and animal neurons – is an area of research that has hugely expanded in the past five years. Proponents say that these systems are yielding important insights into health and disease, but others say the chimeras represent an e ... Show More
23m 31s
Mar 2023
How to build a virus-proof cell
00:47 An edited genetic code that prevents viral infectionResearchers have engineered bacteria with synthetic genomes to be immune to viral infection. The team streamlined the bacteria’s genetic code, and re-engineered the protein-producing machinery to insert the wrong amino aci ... Show More
31m 38s
Jun 2024
The new science of ageing and the quest to live forever
The super-rich are trialling innumerable whacky theories to radically extend their lives, from not eating after 11pm to taking hundreds of supplements a day and even blood transfusions from their children. But what does the science tell us? Could some of these ideas actually prov ... Show More
28m 59s
Jun 2023
Rethinking The Lab Rat
For generations, scientists have leaned on seven key species, including rats and mice, for research. They're called model organisms and they've been standardized over the year — removing as much individuality as possible. But as research questions become more complicated, some re ... Show More
12m 39s