The Filtrate:
Joel Topf
Swapnil Hiremath
Nayan Arora
Priya Yenebere
Special Guests:
Todd Miano, PharmD, PhD @Miano81 Assistant Professor of Epidemiology, Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine.
Show Notes:
Early Pip/Tazo article showing nephrotoxicity. Covered by NephJC
Linazolid vs Vanco RCT showing excess AKI with Vanco. Yes Vance is a lot less toxic than it was in the Mississippi mud days but your attending telling you it is no longer nephrotoxic is wrong. Linezolid in methicillin-resistant Staphylococcus aureus nosocomial pneumonia: a randomized, controlled study and Vancomycin and the Risk of AKI: A Systematic Review and Meta-Analysis.
Vancomycin-Associated Acute Kidney Injury with a Steep Rise in Serum Creatinine
Vancomycin-Associated Cast Nephropathy: Reality or Fantasy?
Molecular Epidemiology of SepsiS in the ICU (MESSI) prospective cohort. Learn about it her: A multibiomarker-based outcome risk stratification model for adult septic shock*
Cystatin C in acute kidney injury
Changing Definitions of Sepsis
Proposed new definitions of AKI incorporating biomarkers: Recommendations on Acute Kidney Injury Biomarkers From the Acute Disease Quality Initiative Consensus Conference. A Consensus Statement in JAMA Network Open
Protective effect of piperacillin against nephrotoxicity of cephaloridine and gentamicin in animals
PulmCrit – Myth-busting the conditional nephrotoxicity of piperacillin-tazobactam by Josh Farkas
Sharp Objects on Good Reads
The Ocean Course at Kiawah Island Golf Resort
Be Real follow me: BeRe.al/kidney_boy
SNL spoof of BeReal