Despite being one of the earliest recognized genetic diseases, many aspects of Huntington’s disease remain shrouded in mystery. This stems in part from our limited grasp on how our own minds work but also from the dark history of Huntington’s disease and the shame and silence that accompanied it for so long. In this episode, we attempt to bring what we know ... Show More
Yesterday
Special Episode: Dr. Alanna Skuse & The Surgeon, The Midwife, The Quack
Imagine yourself as a 17th century English peasant or merchant or noble. Let’s say you’re dealing with some intense stomach pain or a cut on your leg that won’t heal. Where do you turn to for help? Today’s book club episode reveals that the answer depends on your medical needs, y ... Show More
52m 13s
Sep 8
Ep 221 Electroconvulsive Therapy Part 2: A current conversation
This week, we’re picking up where we left off last episode in our exploration of ECT by examining how this therapy is administered, which conditions it’s used for, and what we know about why it works. To start off, we take you through the procedure step-by-step, including prep an ... Show More
58m 21s
Nov 2024
Genetic Leukodystrophies Mimicking CNS Inflammation - Part 1
In the first part of this two-part series, Dr. Justin Abbatemarco talks with Dr. Jennifer L. Orthmann-Murphy about a practical approach to genetic leukodystrophies, focusing on the importance of genetic testing, identifying red flags in patients, and navigating the complexities o ... Show More
25m 41s
Nov 2024
Genetic Leukodystrophies Mimicking CNS Inflammation - Part 2
In the concluding segment of this two-part series, Dr. Justin Abbatemarco talks with Dr. Jennifer L. Orthmann-Murphy about genetic leukodystrophies and the increasing recognition of these disorders in adult neurology, the importance of genetic testing, and the evolving treatment ... Show More
13m 12s
May 2017
#77 — The Moral Complexity of Genetics
Sam Harris speaks with Siddhartha Mukherjee about the human desire to understand and manipulate heredity, the genius of Gregor Mendel, the ethics of altering our genes, the future of genetic medicine, patent issues in genetic research, controversies about race and intelligence, a ... Show More
44m 11s
Mar 2025
Decoding Risk: Understanding Polygenic Risk Scores in Modern Medicine. Demystifying Genetics with Erica Spaeth
<p>This episode dives into polygenic risk testing, exploring how genetic data can inform healthcare strategies. We discuss the complexities of communicating risk, the role of polygenic scores in identifying disease susceptibility, and the evolving landscape of personalized medici ... Show More
49m 41s
Mar 2012
Genes and evolution - from populations to tumours
From whole populations to individual cancers, we're taking a look at genes and evolution. We're also talking about dogs and their diseases, shining a light on Van Gogh's sunflowers, and wondering whether the USB-sized DNA sequence is hope or hype. Plus we've got our gene of the m ... Show More
32m 40s