About this episode
Nov 2
REBOOT #530 Nutrition with Dr. Joan Salge Blake
We have another classic episode for you. Confidently counsel on nutrition, as we discuss different dietary patterns and address common patient queries. We are joined by Dr. Joan Salge Blake (Boston University).Sponsor: Mint MobileCut your wireless bill to 15 bucks a month at MINT ... Show More
1h 15m
Oct 26
#544: Updated Pulmonary Embolism Guidelines
Review the latest 2026 AHA/ACC multisociety pulmonary embolism guidelines with us, including risk stratification, new clinical categories, acute and extended anticoagulation, advanced therapies, follow-ups, and more. We are joined by Drs. Cyrus Askin and Nick Mark from Critical C ... Show More
1h 16m
Oct 19
#543: Navigating Post-Acute Care and Living Options for Older Adults with Dr. Rachel K. Miller
Show description: Learn how to navigate conversations about changing care needs, match older adults with the right site of care, and connect patients and families with resources to make transitions smoother and more successful. We’re joined by Dr. Rachel Miller, to break it all d ... Show More
1h 23m
Jan 2021
Anaphylaxis
<p>This episode covers anaphylaxis.<br/><br/>Written notes can be found at <a href='https://zerotofinals.com/paediatrics/immunology/anaphylaxis/'>https://zerotofinals.com/paediatrics/immunology/anaphylaxis/</a> or in the immunology section of the Zero to Finals paediatrics book.< ... Show More
7m 58s
Sep 2020
Anaphylaxis
Anaphylaxis is a severe, generalised or systemic hypersensitivity reaction. It is characterised by rapidly developing life-threatening airway and/or breathing and/or circulation problems usually associated with skin and mucosal changes. Adriana Andreae, Assistant Professor, Depar ... Show More
19m 31s
Sep 2021
Food Allergies
<p>On this episode, we discuss immunologically mediated adverse reactions that patients can have to foods (food allergies). We provide a brief overview of some background information and pathophysiology. We then review the pharmacological management of an acute allergic reaction ... Show More
49m 1s
May 2020
Hypersensitivity Reactions
<p>A 16 year old male is being seen in the ER for cellulitis and a skin abscess. He has already undergone I & D of the abscess and he's waiting to be discharged. You order a shot of Clindamycin, 600mg to be given IM prior to his discharge. Five minutes later, you're called back i ... Show More
9m 46s
May 2024
Episode 904: Cardiovascular Risks of Epinephrine
2m 11s
Jan 2021
Allergy
<p>This episode covers allergy.<br/><br/>Written notes can be found at <a href='https://zerotofinals.com/paediatrics/immunology/allergy/'>https://zerotofinals.com/paediatrics/immunology/allergy/</a> or in the immunology section of the Zero to Finals paediatrics book.</p><p>The au ... Show More
13m 45s
Apr 2025
Episode 953: Penicillin Allergies
2m 42s
Jan 2024
Episode 274: Anaphylaxis and Other Perioperative Hypersensitivity Reactions with Jonathan Kay
In this 274th episode I welcome Dr. Jonathan Kay (JK) to the show to discuss perioperative hypersensitivity reactions. We focus on the diagnosis and treatment of anaphylaxis and also discuss antibiotic allergies and how to deal with the ever present allergy to PCN. Our Sponsors:* ... Show More
51m 23s
Mar 2023
186. Ring the Alarm: Mast cell activation syndrome (MCAS)
Send us Fan MailToday's episode is all about a rare disease that you may encounter on your allergy and immunology rotation! This episode was written by Dr. Candice Luo (Internal Medicine Resident) and reviewed by Dr. Paul Keith (Allergy and Immunology) and Dr. Zahira Khalid (Gene ... Show More
13m 1s
Recognize common presentations of anaphylaxis and stop under-treating this deadly allergic reaction with tips from Dr. Olajumoke Fadugba, Assistant Professor of Medicine, University of Pennsylvania! We review the basic pathophysiology and the standard criteria for diagnosing anaphylaxis, treatment basics, the primary importance of epinephrine, and the utility of adjunctive therapies. Also included are great tips on counseling patients about auto-injectable epinephrine, and a reminder not to panic…even when you inject your own thumb?! Original show notes
here.
Credits
- Producer, infographic, and cover art: Emi Okamoto MD
- Hosts: Matthew Watto MD, FACP; Stuart Brigham MD, Emi Okamoto MD
- Editor: Matthew Watto MD, FACP
- Guest: Olajumoke Fadugba MD
- Special thanks to Sarah Phoebe Roberts MPH for booking!
Show Segments
- Intro and disclaimer
- Guest one-liner, book recommendation, advice to fellows and trainees
- Case of anaphylaxis with mucocutaneous and GI symptoms
- Anaphylaxis (IgE mediated mast cell action) vs anaphylactoid (non-IgE mediated mast cell activation; e.g. contrast allergy, vancomycin)
- Vancomycin and non-IgE mediated reactions
- Common presentations of anaphylaxis and the three diagnostic criteria
- Biphasic reactions and predicting severity
- Counseling patients on the use of epinephrine
- Stuart’s thumb question
- Adjuvant medications: antihistamines and corticosteroids
- Are there any contraindications to epinephrine use?
- Use of tryptase levels when the diagnosis of anaphylaxis is uncertain
- Outro
Sponsor
<p dir="ltr"><strong>Contributor: Aaron Lessen MD</strong></p> <p dir="ltr"><strong>Educational Pearls:</strong></p> <p dir="ltr">Epinephrine is essential in the treatment of anaphylaxis, but is epinephrine dangerous from a cardiovascular perspective?</p> <p dir="ltr">A 2024 stud ... Show More
<p dir="ltr"><strong>Contributor: Geoff Hogan MD</strong></p> <p dir="ltr"><strong>Educational Pearls:</strong></p> <ul> <li dir="ltr" aria-level="1"> <p dir="ltr" role="presentation">Penicillin allergies are relatively uncommon despite their frequent reports</p> </li> <ul> <li d ... Show More
