TWiV 822: Viking variola variants

Rich reviews the history of smallpox and the discovery of variola viral genomes in ancient DNA from human remains throughout Northern Europe, which pushes back the earliest date of smallpox virus infection to ~600–1050 CE, overlapping the Viking Age.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker

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• Variola virus genomes from Viking era (Science)
• Hidden history of ancient plagues (Nature)
• Was smallpox a mild disease? (Science)
• Smallpox: Ten years gone (Am J Pub Health)
• Myth of the milkmaid (NEJM)
• Interview with DA Henderson (ASM)
• Letters read on TWiV 822
• Timestamps by Jolene. Thanks!

Brianne – The Animal Kingdom is Full of Genetic Screwballs Kathy – Science dresses, accessories from Svaha and Rosalind Franklin’s DNA diffraction dress Rich – The Saxon Stories Alan – Cincinnati’s “Old Cunny,” and audiobook version Vincent – Infectious QBeta viral DNA

Jeff – The unvaccinated may not be who you think

Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv