Sofosbuvir: Chemistry in its element

This week, we explore how molecular glues have revolutionized how we treat previously 'undruggable' cancers and explore how modern scientific techniques are teasing apart the mysteries of one of the most iconic historical artefacts with Phillip Broadwith and Neil Withers. A groun ... Show More

This week, we discuss a study showing promise in applying CAR-T immunotherapy in bladder cancer tumours and breakdown how scientists have uncovered spectral signatures previously misassigned in carbon materials – with Frankie Macpherson and Mason Wakley. CAR-T therapy has been a ... Show More

In this episode, we discuss the changes to science policy made by the new UK prime minister and breakdown the chemistry behind crumbling concrete in Ireland. On July 21, new UK Prime Minister Andy Burnham abolished the government's department of science and absorbing its function ... Show More

Cortisol. What it is and how to better manage your levels to better your health. 

Cortisol is the 'it' hormone of the moment. So many people are talking about cortisol face, cortisol weight gain, cortisol anxiety, but what is cortisols actual function and role and why are many of the myths that surround it, simply not true? In today's episode, we talk cortisol ... Show More

<p>This episode covers the physiology of cortisol and the adrenal axis.<br/><br/>Written notes can be found at <a href='https://zerotofinals.com/physiology/endocrine/cortisol/'>https://zerotofinals.com/physiology/endocrine/cortisol/</a> or in the endocrinology section of the 2nd ... Show More

<p><span data-sheets-root="1" data-sheets-value= "{"1":2,"2":"Ready to banish burnout and stress? Darren Hardy issues unique challenge to counter burnout and the overwhelming effects of high-stress living. This transformative exercise will activate oxytocin, the \"love hormone,\" ... Show More

BONUS on Cosyntropin stimulation tests! What exactly is it? How do you interpret them? What is the difference between adrenal insufficiency and steroid withdrawal syndrome?Use promo code COREIM for 1 month of free access to Glass Pro at https://glass.health/coreim Behind The Scen ... Show More

Steve Kashul and Dr. Cole talk about the benefits, safety and risks of Cortisone Shots. 

This episode I describe the biology of two essential hormones we all make: cortisol and adrenaline (also called epinephrine). Cortisol and adrenaline powerfully regulate our levels of energy, focus and immune system function. I describe various science-supported tools and practic ... Show More

Oxytocin has been called the “love hormone.” But recent research has shown that the brain chemical may play a role in regulating our moral behaviors. Researcher and author Paul Zak, PhD, discusses how his experiments and clinical studies have given us a glimpse into how oxytocin ... Show More