Vaccines are seen as a way out of the coronavirus pandemic; a way to stop transmission and have fewer patients in hospital. Host Nuala McGovern shares different experiences of vaccination and hospitalisation. For some who have been vaccinated, infection is still possible, but hospitalisation is expected to be less likely. Two guests describe their reactions to getting a positive test, after having Covid jabs, and how the virus affected them. We consider too those who are hesitant about the Covid vaccine, despite the dangers of catching the disease.