Maria Agasovna Guleghina (Russian: Mapия Aгacoвнa Гулeгинa, Ukrainian: Марія Агасівна Гулегіна, née Meytardjan (Russian: Мейтарджян); born August 9, 1959) is a soprano opera singer born in Odessa (USSR, now in Ukraine), particularly associated with the Italian repertory.